Democrats plan a filibuster against Neil Gorsuch, President Trump’s nominee to the Supreme Court, setting up a Senate fight that they are almost certain to eventually lose.

The long-expected announcement of the filibuster plan came from Senate Minority Leader Charles E. Schumer (D-N.Y.). In a message on Twitter, Schumer said that Gorsuch would “face a cloture vote,” referring to the Senate process for filibusters.

Democratic vote counters are confident they have more than the 40 votes needed to sustain a filibuster, at least for a time. Currently, 48 senators caucus with the Democrats, including two who were elected as independents.

That leaves Senate Republicans with two paths they could use to confirm Gorsuch.